Stem cells in orthopaedics

Publication date: 16.06.2020

New minimally invasive MSC technique allows the reconstruction of damaged tissues and helps avoid arthroscopic procedures and even transplantation

The use of mesenchymal stem cells (MSC) is currently one of the most promising methods of minimally invasive treatment, with an attempt to restore damaged or degenerated tissues. In traumatology this technique is used mainly to treat acute and chronic post-traumatic changes. The MSC method makes it possible for us to give our patients the opportunity to quickly regenerate and rebuild damaged muscle, fibrous, and bone tissues. In chronic injuries, disorders and delayed healing, this technique  supports and stimulate soft tissues to regenerate and rebuild.

Key benefits:

  • Reduction of pain
  • Restoration or improvement of joint mobility
  • Reduction of painkillers use


  • Injuries to the muscles and tendons, e.g. jumper's knee, damage to a two-headed arm muscle trailer
  • Massive damage to tendon sheaths with instability
  • Chronic injuries with subsequent scars
  • Fresh and chronic damage to articular cartilage (e.g. of knees, ankles, or wrists)
  • Prevention and treatment of early degenerative changes in knee, shoulder, hip and ankle joints
  • Bone fixation disorders and delays
  • Support for treatment of bone fractures (e.g. ankle, tibial or radial)
  • Simultaneous treatment with stabilisation of bone fractures
  • Simultaneous treatment in refraction revision and prosthesis with bone grafts

MSC can be used initially before arthroscopic techniques, chondrocyte or cartilaginous bone grafts. It is also possible to safely administer multiple stem cell transplants – this increases the efficiency of the method and improves the treatment.

What does the procedure look like?

Each of us has carries large resources of these cells – at the Damian Medical Centre, wee isolate them from patient’s own fat tissue. This is currently the method that guarantees the maximum concentration of isolated MSC cells while being more acceptable to the patient than bone marrow removal. Hence, frequently occurring bone marrow pain after bone marrow removal and the risk of infection within the bone marrow are avoided. This method is also technically simpler and safer for patients compared to bone marrow intrusion. The MSC cells taken from the adipose tissue (most frequently, on the medial surface of the thigh) are then prepared, accumulated and prepared for administration given the specific patient’s condition. By using autogenous cells we can minimise the risk of immunological, inflammatory etc. complications. The implantation of isolated cells in sterile conditions and with appropriate analgesia reduces the risk of complications.

The mesenchymal stem cells (MSC) have several functions that provide enormous opportunities for tissue regeneration and remodelling – primarily the ability to self-renew, differentiate, and reproduce. MSC techniques are developing in practically all areas of medicine, especially in orthopaedics and traumatology. MSC can be a source of progenitor cells of osteoblasts, chondroblasts involved in the reconstruction of degenerated and damaged motor organ tissues.

The development of the use of MSC is one of the more forward-looking mini-invasive methods for the effective treatment of injuries and diseases of the locomotor system. Since the completion of patient cartilage regeneration and thus the end of bone growth, it is also a promising method for the prevention and treatment of early osteoarthritis. This particular condition affects the whole human population, and depends only on the age or nature of joints overload.

Qualification for procedure

The patient has a consultation qualifying for the procedure. The procedure is carried out from 2 to 4 weeks from the qualification date as it depends on laboratory tests and anaesthesiology qualification.

At the Damian Medical Centre it is usually a one-day procedure. The doctor together with the patient decide on the best date of consultation after the procedure. Depending on the type of injury, the doctor may recommend rehabilitation after the procedure in order to enable quick return to full efficiency.

Single or multiple administration of MSC depends on the nature of the disease, the extent of tissue damage and the result after the first dose.